Oscillatory structures of blood flow reflect the dynamics of information processes in microvascular networks
Krupatkin, A.I.
Fiziologiia Cheloveka 36(2): 101-113
2010
ISSN/ISBN: 0131-1646 PMID: 20432698 Document Number: 640680
Laser Doppler flowmetry was applied at 30 healthy persons and 57 patients in glabrious skin of the II-nd and V-th fingertips: before and after median or ulnar nerve sutures (n = 29) and after hand sympathectomy (n = 28). Information processes in microvascular networks contain both stationary and oscillatory components. For the first time wavelet-analysis of blood flow oscillatory organization was used to study the dynamics of information processes in microvascular networks. Methodics approach was proposed to estimate the general quantity of information, the valuable and semantic features of different information channels and the information regime (multi-channeled or by resonance). Deficit of both general information quantity and its content (particularly of external information), the decrease of accessibility to information and of system self-organization were typical during denervation syndrome. Semantic information signs changed mainly after sympathectomy. The dynamics of information process reflect the functional significance of microcirculation in the course of nerve regeneration and skin reinnervation. Increment of information quantity with mainly trophic content occurred in the preimpulse stage of nerve regeneration; it corresponds to quantitative development of skin microvascular networks with the purpose of trophic support of reinnervation. Mainly the semantic content of information was modulated at the impulse stage in accordance with increase of homeostatic control intensity. Information peculiarities in the transitional period (from preimpulse to impulse stage) included the decrease of sporadic processes, increase of determinism in the system management, predomination of trophic content assimilation with the increment of own myogenic activity, the possibility of not only multi-channeled regime but resonance also. The anti-entropy significance of information was confirmed.