Application of lamotrigine in bipolar disorder--3T MR spectroscopy follow up (part 1)
Sumegi, A.; Halasz, S.; Kliment, E.
Neuropsychopharmacologia Hungarica a Magyar Pszichofarmakologiai Egyesulet Lapja 12(3): 433-441
2010
ISSN/ISBN: 1419-8711 PMID: 20962363 Document Number: 638275
MR spectroscopy (MRS) is a widely used and useful additional tool in the diagnostic process of several neuropsychiatric disorders. Despite several MRS studies in bipolar spectrum research, establishing a clean image about special metabolite alterations in the disorder still needs further investigation. The first part of this case study presents a bipolar II patient and her first 3T MR spectroscopy in drug-naive conditions, comparing to a healthy subject. Having finished the first MRS investigation, we applied lamotrigine medication. The ongoing second part of the study will show the data of the second MRS scan, after 5 month of lamotrigine therapy.