Pharmacological correction of hypoxic and free-radical disorders in patients with acute myocardial infarction complicated by acute heart failure
Livanov, G.A.; Amagyrov, V.P.; Batotsyrenov, B.V.; Lodiagin, A.N.; Batotsyrenova, K.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 73(5): 12-14
2010
ISSN/ISBN: 0869-2092 PMID: 20597363 Document Number: 638023
Results of the evaluation of clinical findings in a group of 36 patients with acute myocardial infarction (AMI) complicated by acute heart failure (AHF) of class II - IV [according to T. Killip and J. Kimball (1967)] show that the use of cytoflavin and perftoran favors a decrease in the patient critical situation length, duration of patient's stay in hospital, and lethality level. It is established that these drugs lead to a decrease in the depth of hypoxia and lipid peroxidation in tissues, improves oxygen utilization, and restores antioxidant system activity in AMI/AHF patients.