Advances in the study of regulation of novel organic cation transporter-2
Wang, F.-R.; Guo, R.-C.
Yao Xue Xue Bao 44(10): 1061-1065
2009
ISSN/ISBN: 0513-4870 PMID: 20055125 Document Number: 637239
Novel organic cation transporter-2 (OCTN2), a member of the organic cation transporter family, may transport carnitine and multiple organic cationic drugs. Thus OCTN2 possesses substantial roles in physiology and pharmacology. A number of researches have proven that many factors can regulate the expression and/or function of OCTN2 via different pathways, and then may affect the homeostasis and disposition of drugs. This paper reviews recent progresses in this field.