Recent advances in the applications of ultrasonic microbubbles as gene or drug vectors
Shen, Y-Yuan.; Gao, Z-Gao.; Rapoport, N.
Yao Xue Xue Bao 44(9): 961-966
2009
ISSN/ISBN: 0513-4870 PMID: 20055169 Document Number: 636410
With the research and application of the new ultrasound microbubble contrast agents, ultrasonic microbubbles can not only help to image, but they can also be used as genes or drug carriers. The microbubbles as genes or drug carriers can pass across the endothelial cell barrier and release genes and drug under the action of ultrasound field, which achieve target treatment effect. Based on the relevant materials, the bioeffects, early successes with gene and drug delivery, and potential clinical applications are reviewed.