Resection of a giant malignant mediastinal peripheral nerve sheath tumour under cardiopulmonary bypass

Su, J.W.; Chua, Y.L.; Ong, B.H.; Lim, C.H.

Singapore Medical Journal 50(6): e199-e200

2009


ISSN/ISBN: 0037-5675
PMID: 19551295
Document Number: 635667
Malignant peripheral nerve sheath tumour (MPNST) is a rare occurrence in the mediastinum. It is biologically aggressive and is generally resistant to chemoradiation therapy. The mainstay of treatment is complete surgical resection. We report a large MPNST which invaded into the adjacent aortic wall in a 50-year-old man. Extensive resection, which included aortic reconstruction under cardiopulmonary bypass and deep hypothermic arrest, was necessary for a good long-term outcome.

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