Malignant tumors of the peripheral nerve sheath (MPNST) after irradiation
Dini, M.; Caldarella, A.; Lo Russo, G.; Conti, P.
Pathologica 89(4): 441-445
1997
ISSN/ISBN: 0031-2983 PMID: 9471614 Document Number: 479700
A case of relapsed malignant tumor of the brachial plexus and its nervous roots (MPNST) was observed in a patient treated with radiotherapy for Hodgkin's disease 24 years previously. A known risk of radiation therapy is the induction of secondary neoplasms, less commonly malignant peripheral nerve sheath tumor (MPNST). The clinico-pathological features of this rare tumor are presented and the possible relationship between radiotherapy and MPNST is discussed.