Anti H.pylori IgM in symptomatic and asymptomatic population

Sumona, A.A.; Hossain, M.A.; Musa, A.K.; Shamsuzzaman, A.K.; Mahmud, M.C.; Khan, M.S.; Ahmed, S.; Begum, Z.; Zahan, N.A.; Ahmed, M.U.; Debnath, C.R.; Anne, R.A.

Mymensingh Medical Journal Mmj 18(1): 18-20

2009


ISSN/ISBN: 1022-4742
PMID: 19182743
Document Number: 634922
To evaluate the usefulness of specific IgM in the diagnosis of Helicobacter pylori infection, a cross sectional study was carried out in the Department of Microbiology, Mymensingh Medical College between July 2006 to June 2007. A total of 45 patients having upper gastrointestinal symptoms underwent endoscopy and were subsequently diagnosed as patients with gastritis, peptic ulcer (PU) and non-ulcer dyspepsia (NUD) and another 45 asymptomatic individuals aged 18-65 years, were included in the study. The serum samples of participants were tested for presence of anti-H pylori IgM by using ELISA method. The ELISA for anti H. pylori IgM provided sensitivity and specificity of 73.33%, 93.33% respectively.

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