Dose-dependent effects of neuroimmunomodulator interferon alpha on behavior of humans and animals
Loseva, E.V.; Loginova, N.A.; Akmaev, I.G.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 95(12): 1397-1406
2009
ISSN/ISBN: 0869-8139 PMID: 20141049 Document Number: 634874
The review analyses the literature on polyfunctional activity of the cytokine interferon-alpha (IA) which has neuroimmunomodulatory properties and is used for treatment of viral and oncologic diseases. The major intention is devoted to action of small and high doses of IA on different forms of animals and human behavior. We suggest that chronic treatment with small IA doses is more effective than high dose therapy.
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