Surgical treatment in advanced endometrial carcinoma
Li, Q.-S.; Li, D.-P.; Wu, X.-R.; Sheng, X.-G.; Zhang, X.-L.; Song, Q.-Q.
Zhonghua Fu Chan Ke Za Zhi 44(10): 750-753
2009
ISSN/ISBN: 0529-567X PMID: 20078961 Document Number: 632448
To study the clinical value of operation in advanced endometrial carcinoma. A retrospective study was carried out in 78 patients with advanced endometrial carcinoma received operation in our hospital from Jan.1, 1997 to Dec. 31, 2007. The basic operation procedures were included total hysterectomy, adnexectomy, omentectomy, appendectomy and resection of metastatic lesions located in abdomino-pelvic cavity. The criteria of satisfied operation was considered that the sizes of residual leision was smaller than or equal to 2 cm, which was used to evaluate the effect of operation. The prognostic factors were also analyzed. Among the 78 cases, the rate of ideal cytoreductive surgery was 83% (65/78), included 23 cases of no residual leisions, 42 cases of residual leisions size smaller than or equal to 2 cm, while 13 cases of residual leisions size larger than 2 cm. The survival rate of 1-year, 3-year and 5-year were 91% (61/67), 55% (28/51) and 28% (10/36), respectively. The results by single factor analysis shown that the survival rate were correlated with prognostic factors included extent of disease, ascites, size of residual lesions, circles of chemotherapy. It is important value for advanced endometrial carcinoma to ideal cytoredutive surgery followed by combined chemotherapy, while radiotherapy no further therapeutic effects.