The multi-target drugs and their design
Jiang, F.-c.
Yao Xue Xue Bao 44(3): 282-287
2009
ISSN/ISBN: 0513-4870 PMID: 19449525 Document Number: 629343
The reduce of bioactivity and augment of the side effect of single-target drugs is generated by the multi-factorial properties of the pathogenesis of disease, which could be solved by the multi-target drugs. The problems and its solution of the design of the multi-target drugs were discussed in this paper, at the same time, the design of the multi-target drugs by pharmacophore model method is presented.
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