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Profile Comparer: a program for scoring and aligning profile hidden Markov models

Madera, M.

Bioinformatics 24(22): 2630-2631

2008

ISSN/ISBN: 1367-4803
PMID: 18845584
DOI: 10.1093/bioinformatics/btn504
Document Number: 626804
Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint files. This application note provides a brief description of the profile-profile algorithm used by PRC. The C source code licensed under the GNU General Public Licence and Linux and Mac OS X binaries can be downloaded from http://supfam.org/PRC. Supplementary data are available at Bioinformatics online.

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