Blood pressure response to antihypertensive agents related to baseline blood pressure
Sermswan, A.; Uboldejpracharak, Y.; Suthichaiyakul, T.; Sukontasarn, A.; Buranakitcharoen, P.
Journal of the Medical Association of Thailand 85(10): 1113-1120
2002
ISSN/ISBN: 0125-2208 PMID: 12501904 Document Number: 6256
Prevalence of white-coat hypertension varies approximately 20 per cent among mild hypertensives. When white-coat hypertensives are prescribed antihypertensive medication, there is usually a decrease in clinic blood pressure (BP), but little or no change in 24 hours blood pressure (ABPM). The objective of the study was to test the hypothesis that efficacy of medication therapy for hypertension is identical in any grading of severity of baseline blood pressure. The authors retrospectively analysed ABPM data from mild to moderate hypertensive patients. Efficacy in decreasing blood pressure by antihypertensives has linear relation to baseline blood pressure. Response to antihypertensive agents in white-coat hypertension is minimal but a significant effect still persists and the possibility of hypotensive adverse events from medication in the case cannot be overlooked.
Document emailed within 1 workday
