Clinical case of the month. Antibiotics and hemodialysis: three cases of neurotoxicity from Maxipime
Parotte, M.C.; Krzesinski, J.M.
Revue Medicale de Liege 63(3): 119-121
2008
ISSN/ISBN: 0370-629X PMID: 18561766 Document Number: 622341
The metabolism of drugs is altered in dialysed patients. We report three clinical cases of neurological toxicity from cefepime in dialysed patient. This molecule can induce in renal insufficiency patients various reversible neurological manifestations like metabolic encephalopathy, myoclonies, or a state of status epilepticus that mimics sometimes a coma in spite of adequate dosing.
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