Periodic fever as the only presenting symptom of multiple myeloma in a young man
Trakatelli, C.; Kintiraki, E.; Koratzis, J.; Gamvrili, L.; Kotsis, V.; Sion, M.
Journal of Biological Regulators and Homeostatic Agents 22(4): 263-265
2008
ISSN/ISBN: 0393-974X PMID: 19036229 Document Number: 622320
We describe a 30-year-old male patient presenting with periodic fever. The patient underwent a series of laboratory tests, X-rays and CT scans. Quantitative immunoglobulin showed IgG 3210.00 mg/dl, IgA 20.00 mg/dl and IgM 27.70 mg/dl. Serum protein electrophoresis revealed a peak with a broad gamma band. Immunofixation revealed an immunoglobulin G -lambda monoclonal component. A bone marrow biopsy established the presence of multiple myeloma. To our knowledge, a periodic 24-hour-lasting fever as the only presenting symptom of multiple myeloma has never been reported.