Research of high frequency induced thermotherapy efficiency for treatment of hepatocellular carcinoma
Lu, L.-G.; Hu, B.-S.; Li, Y.; Luo, P.-F.; Chen, X.-M.
Zhonghua Yi Xue Za Zhi 88(23): 1618-1620
2008
ISSN/ISBN: 0376-2491 PMID: 19035101 Document Number: 622005
To investigate the effectiveness of high frequency induced thermotherapy in the treatment of hepatocellular carcinoma. We included a 65 proven cases of hepatocellular carcinoma in which the diagnosis was confirmed by pathology, radio-imaging and AFP value. The patients were randomly divided into 2 group by odd or even hospitalization number. A total of 32 patients were enrolled in the TACE + PEI only group and 33 patients were enrolled in the TACE + HITT therapy group. For the 32 patients in TACE + PEI only therapy group, the 1, 2, and 3 year of survival rates were 73%, 56%, and 23%, respectively, with a median survival of 1.876 years. For patients in the therapy group, the 1, 2, and 3 year survival rates were 87%, 76%, and 51%, respectively, with a median survival of 2.134 years. Survival rate and duration in the therapy group was significantly greater in the combination therapy group compared to the control group (P < 0.05). There was a negative correlation between the effectiveness of combination therapy and the mortality risk (P < 0.05). HiTT + TACE can significantly increase survival rate and extend length of survival in patients with hepatocellular carcinoma.