Percutaneous hepatic puncture radio frequency ablation in the treatment of hepatocellular carcinoma
Chen, Y.; Wu, M-chao.; Chen, H.; Zhang, Z-jian.; Gao, Y-tao.
Zhonghua Zhong Liu Za Zhi 25(1): 88-90
2003
ISSN/ISBN: 0253-3766 PMID: 12678998 Document Number: 552472
Objective To observe the curative effect of percutaneous radio frequency ablation (PRFA) on hepatocellular carcinoma. Methods Under local or epidural anaesthesia, radio frequency electrodes were percutaneously introduced with ultrasound guide into the tumor in the liver for ablation. Results Among the 96 hepatic cancer lesions in 60 patients, 41(42.7%) with diameter < 3.5 cm were ablated by one session. The effective rate (CR + PR) was 100% (41/41) with CR 92.6% (38/41) and PR 7.3 % (3/41). During the 6-24 month follow up of these lesions, 36(87.8%)of these 41 patients showed no recurrence by CT or MRI. Fifty-five (57.3%)lesions with diameter 3.5 cm ltoreq PHI < 12 cm were ablated by two or three sessions, with CR 3.6% (2/55), PR 67.3% (37/55) and CR + PR 70.9% (39/55) by CT or MRI in 1 to 3 months after the treatment. Conclusion Percutaneous radio frequency ablation is effective on liver tumor with PHI < 3.5 cm. It is partly effective on lesions with 3.5 cm ltoreq PHI < 12 cm.