Salmonella typhi--time to change empiric treatment

Gade, C.; Engberg, J.ør.; Weis, N.

Ugeskrift for Laeger 170(40): 3133-3134

2008


ISSN/ISBN: 1603-6824
PMID: 18823602
Document Number: 620250
In the present case series report we describe seven recent cases of typhoid fever. All the patients were travellers returning from Pakistan, where typhoid is endemic. Salmonella typhi isolated from the patients by blood culture were reported as intermediary susceptible to fluoroquinolones in six out of seven cases. We recommend that empiric treatment of suspected cases of typhoid fever includes a third generation cephalosporin such as ceftriaxon. Furthermore, the present report stresses the importance of typhoid vaccination of travellers to areas where typhoid is endemic.

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