A new tyrosinase inhibitor from Crinum yemense as potential treatment for hyperpigmentation
Abdel-Halim, O.B.; Marzouk, A.M.; Mothana, R.; Awadh, N.
Die Pharmazie 63(5): 405-407
2008
ISSN/ISBN: 0031-7144 PMID: 18557429 Document Number: 618700
A new pyran derivative, 6-hydroxy-2H-pyran-3-carbaldehyde, has been isolated from the methanolic extract of Crinum yemense along with the known alkaloid haemanthamine, benzoic acid and 1,1'-bis(1,1'-carboxyethyl) ether which is isolated from a natural source for the first time. Structure elucidation of these compounds based on spectroscopic evidences. The pyran derivative was found to be a tyrosinase inhibitor more potent than kojic acid.