Drug evaluation: ranirestat--an aldose reductase inhibitor for the potential treatment of diabetic complications
Giannoukakis, N.
Current Opinion in Investigational Drugs 7(10): 916-923
2006
ISSN/ISBN: 1472-4472 PMID: 17086937 Document Number: 602419
Ranirestat is an orally available aldose reductase inhibitor under development by Dainippon Sumitomo Pharma Co Ltd (formerly Dainippon Pharmaceutical Co Ltd), Kyorin Pharmaceutical Co Ltd and Eisai Co Ltd for the potential treatment of diabetic complications, such as neuropathy, cataracts, retinopathy and nephropathy. Phase III trials were ongoing in February 2006.