Effect of supplemented Taoren Chengqi decoction on NIT-1, a pancreatic beta-cell from a transgenic NOD/Lt mouse
Meng, F-Min.; Zhao, Y-Ying.; Wang, H.; Zhang, Y-Song.; Li, Q-Yan.; Li, L-Ying.; Zhang, Q-Ying.
Zhongguo Zhong Yao Za Zhi 33(13): 1602-1604
2008
ISSN/ISBN: 1001-5302 PMID: 18837325 Document Number: 616969
To study the effect of Supplemented Taoren Chengqi decoction (STCD) on the secretion of insulin and proliferation of NIT-1. The effect of STCD and the serum of rat after orally administrating of STCD on the secretion of insulin and proliferation of NIT-1 were studied. The proliferation of NIT-1 was measured by 3H-TdR incorporation and cell counting methods, while the secretion of insulin was measured from the cultured medium by the ultra sensitive rat insulin ELISIA kit. Both the STCD and the serum of rat after orally administrating of STCD significantly could increased the secretion of insulin and proliferation of NIT-1. The treatment of the diabetic patients by STCD might be through with its improvement of secretion of insulin and proliferation on pancreatic beta-cell.