A dynamic analysis on incidence and trend of HIV-1 epidemics among intravenous drug users, attendants at the STD clinics and pregnant women in Yunnan province, China
Yang, L.; Ma, Y.-l.; Luo, H.-b.; Jia, M.-h.; Yang, C.-j.; Wang, M.-j.; Chen, H.-c.; Shen, S.; Mei, J.-y.; Tian, F.; Shi, Y.-h.; Yan, W.-y.; Lu, L.; Jiang, Y.
Zhonghua Liu Xing Bing Xue Za Zhi 29(12): 1204-1207
2008
ISSN/ISBN: 0254-6450 PMID: 19173964 Document Number: 616679
BED-CEIA assay was used in HIV/AIDS surveillance sentinel sites to identify recent HIV-1 infection, to estimate HIV-1 incidence and to understand the epidemic trends in Yunnan province. Serum specimens were collected from IDUs in sentinel sites, attendants in STD clinics and pregnant women under a cross sectional study from 2000 to 2007. Specimens confirmed as HIV-1 positive were tested with BED-CEIA to find recent HIV-1 infection, then the annual HIV-1 incidence for each group was calculated and the trends of HIV-1 incidence observed. 144 780 serum specimens were collected and 4932 of them were confirmed as HIV-1 positive. 4678 positive specimens were tested with BED-CEIA and 723 ont of them were identified as recent infections. Specimens from the two years were combined for testing. The average HIV-1 prevalence among IDUs was 18.2% - 26.9% from 2000 to 2007 and the annual incidence were 14.65%, 6.21%, 4.06%, 2.23% respectively. The average HIV-1 prevalence among attendants in STD clinics was 1.6% - 3.2% and the annual incidence rates were 1.46%, 0.76%, 0.52%, 0.33% respectively. The average HIV-1 prevalence among pregnant women was 0.2% - 0.5% and the annual incidence rates were 0.16%, 0.11%, 0.10%, 0.09% respectively. HIV-1 incidence rates among IDUs, STDs and pregnant women showed a steady decrease.