HPV prevalence and cervical intraepithelial neoplasia among HIV-infected women in Yunnan Province, China: a pilot study
Zhang, H.-Y.; Tiggelaar, S.M.; Sahasrabuddhe, V.V.; Smith, J.S.; Jiang, C.-Q.; Mei, R.-B.; Wang, X.-G.; Li, Z.-A.; Qiao, Y.-L.
Asian Pacific Journal of Cancer Prevention Apjcp 13(1): 91-96
2012
ISSN/ISBN: 2476-762X PMID: 22502720 Document Number: 561818
To determine the prevalence of HPV and cervical neoplasia among HIV-infected women in southwestern China. Cervical cytology, HPV detection by Hybrid Capture-2™ assay, and diagnostic colposcopy were followed by cervical biopsy if indicated. Logistic regression analysis was used to analyze associations between HPV co-infection and cervical intraepithelial neoplasia (CIN), and HIV-related clinical and laboratory parameters. Colposcopic-histopathologically proven CIN2+ lesions were present in 7/83 (8.4%) HIV-infected women. Nearly half (41/83, 43%) were co-infected with carcinogenic HPV genotypes. HPV co-infection was higher in women with colposcopic-histopathologically proven CIN2+ lesions than women with