Metabolic syndrome: prevalence among outpatients with arterial hypertension, the efficacy of treatment
Nesterov, I.I.; Poltavtseva, O.V.; Lazareva, O.A.; Tepliakov, A.T.
Klinicheskaia Meditsina 86(2): 67-70
2008
ISSN/ISBN: 0023-2149 PMID: 18368798 Document Number: 616446
The purpose of the investigation was to study prevalence of specific variants of metabolic syndrome (MS) in patients with arterial hypertension (AH), and assess the efficacy of antihypertensive therapy in outpatient departments using drug-and non-drug methods. The subjects, 680 patients with MS and I to III degree AH, underwent clinico-anthropometric examination, lipidography, and fasting blood sugar measurement; outpatient and in-patient medical records were analyzed. Various variants of MS were found in 86.7% of the patients. Combination of AH, dyslipidemia, and excessive body weight (BW) was revealed in 32.5% of the patients; the same combination, but with normal BW, was revealed in 19.2% of the subjects; AH with obesity and carbohydrate metabolic disturbances was found in 19.1% of the subjects; AH with excessive BW alone was found in 6.2% of the patients; AH with hyperglycemia and dyslipidemia was revealed in 5.4% of the cases. The study also found that 30% of the patients did not receive any therapy at all, 34.3% received irregular treatment, only 35.7% of the subjects took medications on a regular basis, and only 12.4% of the patients target arterial pressure levels were had been achieved. Thus, the therapy of patients with AH and MS does not meet current requirements. Low patients'compliance with drug- and non-drug therapy and the fact that physicians do not follow scientifically based standards of treatment are the main reasons for the low efficacy of AH treatment.