New information for thoracic surgeons on the pathogenesis of acute exacerbation of interstitial pneumonias
Ebina, M.
Kyobu geka. Japanese journal of thoracic surgery 60(10): 919-925
2007
ISSN/ISBN: 0021-5252 PMID: 17877013 Document Number: 613689
For the thoracic surgeons, the difficulty in the treatment of patients with interstitial pneumonias may exist in the frequent onset of acute exacerbation after thoracic surgery for lung resection or lung biopsy. The pathogenesis of acute exacerbation is dependent on the remodeling of secondary lobules by fibrosis which induces alveolar-capillary lesions and disruption of superficial lymphatics in these interstitial pneumonias. The understanding of this new pathogenesis of the onset of acute exacerbation of interstitial pneumonias may enable us to prevent and treat this refractory status effectively.