Ultrastructural characteristics of gastric mucosal epithelial cells of AIDS patients complicated with chronic gastritis
Zhang, B.; Jin, R.
Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 21(1): 17-19
2007
ISSN/ISBN: 1003-9279 PMID: 17429524 Document Number: 612826
To investigate ultrastructural features of gastric mucosal epithelial cells of AIDS patients complicated with chronic gastritis. Ten AIDS patients with alimentary tract symptoms underwent gastroscopy and biopsy of gastric mucosa was performed by random method. All the biopsy specimens were examined by electron microscopy. There were swelling, vacuolar degeneration and increased density of mitochondria, dissociated ribosomes in the cytoplasm, and dilation of rough endoplasmic reticulum and Golgi's apparatus. Some gastric mucosal cells were in different stages of apoptosis. The gastric mucosal cells of the control subjects with chronic gastritis but without AIDS showed swelling of mitochondria to different extents and necrosis of epithelial cells. Injuries of gastric mucosal epithelial cells of AIDS patients complicated with chronic gastritis may be more severe than those seen in the control subjects and the mechanism of the more severe injuries is unclear.