Diagnosis of adult-onset Still's disease: contribution of biology
Garcia-Hejl, C.; Vest, P.; Garcia, C.; Renard, C.; Revenant, M.C.; Thefenne-Astier, H.; Berets, O.
Annales de Biologie Clinique 65(3): 303-307
2007
ISSN/ISBN: 0003-3898 PMID: 17502305 Document Number: 612350
We report one case of adult-onset Still's disease. The diagnosis of this disease currently requires application of Yamaguchi's criteria and then exclusion of infectious, haematological, autoimmune and neoplasic disorders. The place of biology is enhanced with the use of new markers like ferritin and glycosylated ferritin. Low percentage of glycosylated ferritin (<20%) in presence of very high level of ferritin, unexplained prolonged fever with leukocytosis can help to diagnosis. However, glycosylated ferritin is not yet of in routine use.