Validation the haplotype polymorphisms of the DXS7424-DXS101 on X-chromosome

Yu, B.; Tuo, Y.; Gui, H.-s.; Li, S.-b.

Fa Yi Xue Za Zhi 23(5): 342-344

2007


ISSN/ISBN: 1004-5619
PMID: 18175571
Document Number: 611855
To validate the genetic characteristics and distribution of DXS7424-DXS101 on X chromosome in Han population. DXS7424 and DXS101 loci were genotyped by PCR, PAGE and silvers stain methods. Their genetic parameters were analyzed by Arlequin software. There were 37 haplotypes detected in 151 Han unrelated males. The frequencies ranged from 0.0066 to 0.1391, with a GD value of 0.9453 and a DP value of 0.9389. Haplotypes 16-23 were the most common haplotypes in Han population. Analysis of combined DXS7424 and DXS101 haplotypes appears to be a powerful means in population genetics and forensic practice for determination of identity and paternity.

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