The role of HPV DNA in the evaluation and follow-up of asymptomatic male sexual partners of females with CIN3
Bar-Am, A.; Niv, J.
European Journal of Gynaecological Oncology 28(3): 207-210
2007
ISSN/ISBN: 0392-2936 PMID: 17624088 Document Number: 610807
Purpose: To determine whether and how asymptomatic sexual partners of females with high-grade cervical intraepithelial neoplasia (CIN3) lesions should be examined. Methods: Sexual partners of females with CIN3 were evaluated for HPV-related lesions by scraping samples for high-risk HPV DNA and androscopy (colposcopic inspection of the penis, scrotum and peri-anal area). Abnormal androscopically detected lesions were sampled for cytology by Pap smears. Results: 74 partners of 87 females were studied and underwent androscopy, and 17 (22.9%) had abnormal findings: 11/74 had clinical genital condyloma acuminata and 6/74 had aceto-white lesions on the penile shaft or scrotum. Cytology of the 17 abnormal androscopies showed that six smears were normal and I I had atypia and koilocytosis. Positive high-risk HPV DNA indicated that 13/74 (17.5 %) were infected with HPV. Two partners (2/74, 2.8%) had concomitant HPV DNA 16. Conclusions: Male sexual partners of females with CIN3 should undergo androscopy and cytology of colposcopically detected abnormal areas.