Postoperative diabetes insipidus after transsphenoidal resection of pituitary tumor
Tao, J.; Wen, W-Ping.; Lei, W-Bin.; Chen, Z-Ping.; Su, Z-Zhong.; Mu, Y-Gao.; Xu, G.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 42(3): 199-201
2007
ISSN/ISBN: 1673-0860 PMID: 17633279 Document Number: 610218
To study the prevention and treatment of postoperative diabetes insipidus after removal of pituitary tumor through transsphenoidal operation, to decrease the incidence of postoperative complications and improve the treatment of pituitary tumor. The clinical data of 86 cases of transsphenoidal resection of pituitary tumor in recent 8 years were retrospectively reviewed, including 35 endoscopic operation and 51 microscopic operation. The incidence, prevention and treatment of diabetes insipidus were statistically analysed. There were 18 cases of postoperative diabetes insipidus in total of 86 operations, including 15 acute cases, 3 delayed cases. Twelve were temporary , which recovered within 1 week. After prompt treatment, 14 recovered within 1 week, 4 recovered within 2 weeks. No persistent diabetes insipidus was found. The key points to prevent postoperative diabetes insipidus lay in the improvement of operative skills, careful protection during operation and avoidance of unnecessary injury. In case of diabetes insipidus occurred, rational use of antidiuretics and correction of electrolyte balance were effective in the treatment of postoperative diabetes insipidus.