Yolk sac tumor of the vagina
Mahzouni, P.; Pejhan, S.; Ashrafi, M.
Saudi Medical Journal 28(7): 1125-1126
2007
ISSN/ISBN: 0379-5284 PMID: 17603725 Document Number: 609763
Malignant germ-cell tumors (GCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumors (EST) form the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. A mass was palpable anteriorly on rectal examination. Computed tomography showed a tumor mass posterior to the bladder. A biopsy revealed a vaginal EST The serum alpha-fetoprotein was elevated. Vaginohysterectomy was carried out. She was subsequently referred to the oncologist for further management.