Localization of bcl-2 antiapoptotic protein in the human placenta
Korzhevskiĭ, D.E.; Otellin, V.A.; Starorusskaia, A.N.; Pavlova, N.G.
Morfologiia 132(6): 75-76
2007
ISSN/ISBN: 1026-3543 PMID: 18411730 Document Number: 609680
The aim of this investigation was to study the distribution of bcl-2 antiapoptotic protein in various structures of human placenta using immunocytochemical methods. Syncytiotrophoblast was found to have the greatest bcl-2 immunoreactivity, while cytotrophoblastic elements, connective tissue cells of the villi and the blood vessel walls were bcl-2-negative. It is suggested that accumulation of bcl-2 in the syncytiotrophoblast may reflect its high resistance to detrimental factors.