Effects of dietary intervention on weight loss and improvement of metabolic cormorbidities in a population of obese adults
Rached-Amrouche, C.; Jamoussi-Kammoun, H.; BLouza-Chabchoub, S.
La Tunisie Medicale 85(2): 102-104
2007
ISSN/ISBN: 0041-4131 PMID: 17665653 Document Number: 608398
Weight loss improves most of the comorbidities associated with obesity. The purposes of this study are to determine the effects of dietary intervention and physical activity on weight management and to evaluate the beneficial effects of weight loss on metabolic profile of obese adults. This prospective study concerned 24 obese and overweight patients recruited between 2003-2004. They have undergone a 6 months period of personalized diet and physical exercise. Average weight loss achieved at 6 months was 6.8 +/- 5.6 kg (P < 10). Mean fat mass reduction was 3.05 +/- 6.2% (P = 0.02) and average waist circumference reduction was 7.55 +/- 5.21 cm (P < 10(-3)). This improvement in anthropometric parameters reduced significantly fasting glycaemia (-0.58 +/- 0.87 mmol/l, P = 0.01), total cholesterol levels (- 0.37 +/- 0.69 mmol/l, P = 0.03), triglyceridemia (- 0.39 +/- 0.45 mmol/ l, P = 0.004) and increased HDL-Cholesterol levels (+ 0.1 +/- 0.38 mmol/l, P = 0.05). These results emphasize the urgent need to develop national strategies for the prevention and the management of overweight and obesity. Hence, we can improve metabolic abnormalities usually associated with obesity and reduce cardiovascular risk factors.