Replacement of dietary fat by sucrose or starch: effects on 14 d ad libitum energy intake, energy expenditure and body weight in formerly obese and never-obese subjects
Raben, A.; Macdonald, I.; Astrup, A.
International Journal of Obesity and Related Metabolic Disorders Journal of the International Association for the Study of Obesity 21(10): 846-859
1997
ISSN/ISBN: 0307-0565 PMID: 9347402 Document Number: 471166
OBJECTIVE: To investigate the impact of a high-sucrose diet vs a high-starch and a high-fat diet on 14d ad libitum energy intake, body weight, energy expenditure and sympathoadrenal activity. MEASUREMENTS: Food intake; body weight and composition (bioelectrical impedance); 24h energy expenditure, substrate oxidation rates, spontaneous physical activity, heart rate and appetite sensations in a respiration chamber (VAS scores); plasma catecholamine concentration and blood pressure. closely matched controls (BMI: 22.6 +- 0.4 kg/m-2). were observed on the fat or sucrose diets. After 14d on the sucrose diet, 24h energy expenditure as well as postprandial plasma adrenaline and noradrenaline concentrations, were significantly increased compared with the other two diets. Overall satiety and palatability ratings were also highest on the sucrose diet. CONCLUSION: Intake of a 14-d ad libitum high-starch diet decreased energy intake and body weight compared with a high-fat or high-sucrose diet. The increased energy expenditure observed on the sucrose-rich diet can probably be explained both by the increased intake of energy and fructose (mainly from sucrose) on this diet.