Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature
Martinez, J.B.; Valero, J.S.; Bautista, A.J.; Restrepo, J.F.; Matteson, E.L.; Rondon, F.; Iglesias-Gamarra, A.
Clinical and Experimental Rheumatology 25(1): 47-53
2007
ISSN/ISBN: 0392-856X PMID: 17417990 Document Number: 606205
To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies. Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies. The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor. Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.