Studies on HPLC fingerprint of cortex moutan
Xu, S.-J.; Li, P.; Yang, L.; Zhang, M.; Wang, Z.-T.
Zhongguo Zhong Yao Za Zhi 31(20): 1677-1680
2006
ISSN/ISBN: 1001-5302 PMID: 17225532 Document Number: 604649
To establish a HPLC fingerprint for quality evaluation of Cortex Moutan. The HPLC chromatographic fingerprinting of 30 lots of Cortex Moutan was established and major peaks were identified by LC-MS and MS-MS. The HPLC fingerprint of Cortex Moutan was established, showing 15 characteristic peaks. The areas of these peaks were found to complied with the following rule: paeonol > 1, 2, 3, 4, 6-penta-O-galloyl-glucos > methyl gallate > galloylpaeoniflorin > gallic acid > oxypaeoniflorin > other compounds. The chromatographic fingerprinting of Cortex Moutan with high specificity can be used to control its quality and monitor lot to lot consistency.