Surfing on prothymosin alpha proliferation and anti-apoptotic properties
Letsas, K.P.; Frangou-Lazaridis, M.
Neoplasma 53(2): 92-96
2006
ISSN/ISBN: 0028-2685 PMID: 16575463 Document Number: 604273
Prothymosin a is an extremely abundant nuclear oncoprotein-transcription factor essential for cell cycle progression and proliferation that has been recently suggested as an anti-apoptotic factor. Similarly to other oncoproteins, prothymosin a is overexpressed in a variety of cancer tissues and cell lines. The present review highlights on the proliferation and anti-apoptotic properties of prothymosin a and its possible role in cancer development.
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