Comparative analysis of efficacy of certain neuroprotectors in ischemic stroke
Skorokhodov, A.P.; Dudina, A.A.; Kolesnikova, E.A.; Koron, A.E.; Kobantsev, I.A.; Sedova, A.A.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova Suppl 17: 52-56
2006
ISSN/ISBN: 1997-7298 PMID: 18193579 Document Number: 603584
Cortexin, nootropil and cerebrolysin have been used as neuroprotective medications in the acute period of ischemic stroke (IS). Clinical efficacy of cortexin and nootropil has been compared in 2 therapeutic series in 35 patients and that of cortexin and cerebrolysin--in 45 patients. The efficacy was assessed using several clinical and psychometric scales with statistical processing of the results. The data obtained suggest that in patients with moderate IS the drugs exert a similar and rather marked effect which was stronger comparing to the treatment without these drugs. At the same time, a domestic neuroprotector cortexin has some advantages, especially with regard to the absence of side-effects and "price-dose-therapeutic effect" criterion.