The specific IgE responses to three cockroach strains antigens in patients with asthma
Guo, Y.-s.; Xu, Y.-p.
Zhonghua Nei Ke Za Zhi 45(7): 556-558
2006
ISSN/ISBN: 0578-1426 PMID: 17074109 Document Number: 602854
The purpose of the present study was to determine the cross-reactive allergens from three strains of cockroach (Periplaneta americana, Periplaneta fuliginosa and Blattella germanica) by human serum specific IgE (sIgE) in allergic asthma. The allergens were extracted from Periplaneta americana, Periplaneta fuliginosa and Blattella germanica respectively. Serum sIgE of allergic asthma was determined with ELISA. The sIgE positive rates to Periplaneta americana, Periplaneta fuliginosa and Blattella germanica were 23.5%, 16.0% and 14.0% respectively. The reactive coincidence rate between Periplaneta americana and Periplaneta fuliginosa was 74.0%. The reactive coincidence rate between Periplaneta americana and Blattella germanica was 73.5%. The reactive coincidence rate between Periplaneta fuliginosa and Blattella germanica was 85.0%. The sIgE positive rates of the head and the body of Periplaneta americana were 17.5% and 14.5% respectively. The sIgE positive rates of the head and the body of Periplaneta fuliginosa were 12.5% and 10.5% respectively. The reactive coincidence rate between head and body of Periplaneta americana was 86.0%. The reactive coincidence rate between head and body of Periplaneta fuliginosa was 88.0%. There were some cross-inhibition among the three strains of cockroach according to ELISA cross-inhibition test. Cockroach is one of the main allergens which cause allergic asthma. There exists significant cross-reactive allergic components in the three strains of cockroach and between the head and the body of Periplaneta fuliginosa and Periplaneta americana.