Cholesterol atheroembolic disease in kidney allografts--case report and review of the literature

Schönermarck, U.; Guba, M.; Weiss, M.; Illner, W.D.; Arbogast, H.; Bosch, T.

Clinical Nephrology 66(5): 386-390

2006


ISSN/ISBN: 0301-0430
PMID: 17140169
Document Number: 600764
Cholesterol atheroembolic renal disease is a rare cause of renal allograft dysfunction. Two recipients of cadaveric kidney transplantats from the same donor are discussed with presumed graft failure due to cholesterol emboli of donor origin. A review of the literature summarizes the reported cases in renal transplant recipients. While cholesterol embolization of presumed donor origin seems to have a poor renal outcome, cholesterol emboli originating in the recipient have a more favorable prognosis. As donors and recipients of increasing age or prominent atherosclerosis are accepted for transplantation, cholesterol atheroembolic renal disease may become more prevalent and should be considered in patients with renal allograft dysfunction.

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