Renal amyloidosis complicating Crohn's disease: report of two cases and review of literature
Elloumi, H.; Ben Slama, A.; Arfaoui, D.; Ghouma, M.; Sfar, S.; Ajmi, S.
La Tunisie Medicale 84(4): 253-255
2006
ISSN/ISBN: 0041-4131 PMID: 16832997 Document Number: 599307
Secondary amyloidosis is caused by the extracellular store of the fragment AA of the circulatory protein in serum amyloid-A. It can complicate diseases such as family mediterranean fever, rheumatoid arthritis or Crohn's disease. Renal amyloidosis is a rare but serious complication of Crohn's disease. We report two cases of Crohn's disease associated with a nephrotic syndrome due to renal amyloidosis. It is important to recognize this complication, especially since Colchicine has been proposed as a possible treatment. So, the search for proteinuria seems to be important for an early diagnosis of renal amyloidosis in Crohn's disease.