Contemporary experimental models of traumatic brain injury
Manvelyan, H.
Georgian Medical News 140: 13-16
2006
ISSN/ISBN: 1512-0112 PMID: 17179579 Document Number: 598414
This review article aims to bring investigators' attention to experimental models of traumatic brain injury, widely employed in research in western countries and almost unknown in Eastern Europe. We describe the most successful animal models that cause neurotrauma by applying mechanical energy to the head, skull or dura. It attempts to provide a short compendium of the main characteristics of each of these experimental models of TBI in respect to main human neurotrauma features, histological findings and behavioral impairment in neurologic motor and cognitive function.