The manufacture of synthetic non-sintered and degradable bone grafting substitutes
Gerike, W.; Bienengräber, V.; Henkel, K-O.; Bayerlein, T.; Proff, P.; Gedrange, T.; Gerber, T.
Folia Morphologica 65(1): 54-55
2006
ISSN/ISBN: 0015-5659 PMID: 16783737 Document Number: 598151
A new synthetic bone grafting substitute (NanoBone((R)), ARTOSS GmbH, Germany) is presented. This is produced by a new technique, the sol-gel-method. This bone grafting substitute consists of nanocrystalline hydroxyapatite (HA) and nanostructured silica (SiO). By achieving a highly porous structure good osteoconductivity can be seen. In addition, the material will be completely biodegraded and new own bone is formed. It has been demonstrated that NanoBone((R)) is biodegraded by osteoclasts in a manner comparable to the natural bone remodelling process.