Mechanisms for survival of bacteria in oxidative stress and iron ions deficiency

Sgibnev, A.V.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2006(4): 20-22

2006


ISSN/ISBN: 0372-9311
PMID: 16941863
Document Number: 597674
The influence of culture medium Fe2+ content on the resistance of Escherichia coli to hydroxyl radicals formed in the presence of Fe2+ and hydrogen peroxide in Fenton reaction was investigated. It was founded that a lack of Fe2+ in a culture medium increased resistance of bacteria to hydroxyl radicals but not to hydrogen peroxide. The suggestion was made that the lack of Fe2+ starts up synthesis of metabolites which inactivate hydroxyl radical or block Fe2+ ions participating in Fenton reaction. The phenomenon under study is considered to be a possible mechanism for survival of bacteria in oxidative stress and iron ions deficiency.

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