Feasibility of correction of insulin insufficiency after autotransplantation of splenic tissue in duodenopancreatectomy
Timerbulatov, V.M.; Faiazov, R.R.; Khasanov, A.G.; Rakhmatullin, S.I.; Timerbulatov, S.V.; Saiapov, M.M.
Khirurgiia 2006(3): 21-26
2006
ISSN/ISBN: 0023-1207 PMID: 16710236 Document Number: 596278
Autotransplantation of splenic tissue in two patients after total duodenopancreatectomy and splenectomy for trauma of the duodenum and pancreas has demonstrated positive results and stable compensation of insulin insufficiency in two cases. Experimental studies of autotransplantation of splenic tissue carried out on 20 cats and 100 rats with pancreatectomy- and alloxan-induced diabetes demonstrated good results too. This method may be regarded as the variant of repair therapy with stromal stem-cells of the spleen.