News about phosphorus metabolism
Delanaye, P.; Krzesinski, J.M.
Revue Medicale de Liege 60(3): 189-197
2005
ISSN/ISBN: 0370-629X PMID: 15884702 Document Number: 593880
Phosphorus is mainly present in the serum as phosphate which is the principal intracellular anion, essential for the organism, in particular through its role in the production of ATP. In plasma, only inorganic phosphorus (Pi) is measured. In this article, we will review new information about the regulation of Pi at the intestinal, osseous and mainly renal levels. The various cotransporters sodium-phosphorus (Na-Pi) will also be examined and the molecular regulation mechanisms approached. Finally, illustration of Pi physiology will be given through various clinical examples.