Effect of prostaglandin E2 for cervical priming on fetal hemodynamics
Fok, W.Yee.; Leung, T.Yeung.; Tsui, M.H.Y.; Leung, T.Ngong.; Lau, T.Kin.
Journal of Reproductive Medicine 50(9): 697-700
2005
ISSN/ISBN: 0024-7758 PMID: 16363758 Document Number: 590836
OBJECTIVE: To assess the effect. of the prostaglandin E-2 (PGE(2)) on fetal vascular blood flow during cervical priming.STUDY DESIGN: In a prospective, observational study, 32 pregnant women >= 37 weeks of gestation requiring PGE(2) for induction of labor were recruited. The resistance indices (RIs) of umbilical artery, middle cerebral artery, renal artery and ductus venosum were measured before, 2 and 4 hours after insertion of a PGE(2) vaginal pessary.RESULTS: There were no significant changes in RIs of various fetal vessels during cervical priming with PGE,CONCLUSION: There was no significant change in fetal hemodynamics after vaginal prostaglandin administration. This finding provides further evidence to support the safety of prostaglandin for normal fetuses.