The BCR signalosome: where cell fate is decided
Ulivieri, C.; Baldari, C.T.
Journal of Biological Regulators and Homeostatic Agents 19(1-2): 1-16
2005
ISSN/ISBN: 0393-974X PMID: 16178270 Document Number: 590577
B cell antigen receptor (BCR) engagement results in the assembly of a multimolecular complex at the cytosolic side of the plasma membrane, known as signalosome. Here we briefly review the current knowledge on the molecules which participate in the BCR signalosome and on the response modulators which control the final signal output by enhancing or dampening BCR signaling.