Serotonin syndrome and rhabdomyolysis in venlafaxine poisoning: a case report
Hanekamp, B.B.; Zijlstra, J.G.; Tulleken, J.E.; Ligtenberg, J.J.M.; van der Werf, T.S.; Hofstra, L.S.
Netherlands Journal of Medicine 63(8): 316-318
2005
ISSN/ISBN: 0300-2977 PMID: 16186642 Document Number: 590576
Newer, more selective, antidepressant agents are increasingly being used as first-line treatment. However, clinical experience in patients after a deliberate overdose is limited. We present a case of venlafaxine intoxication complicated by a late rise in creatine kinase, seizures and serotonin syndrome. Rhabdomyolysis prolonged the hospital stay in our patient but had no other serious consequences. Physicians should be aware of this late phenomenon in patients with venlafaxine poisoning.