Antibiotic administration in preterm delivery
Pieta-Dolińska, A.; Jaczewski, B.ł; Wardecka, J.; Woźniak, P.; Wilczyński, J.; Krasomski, G.; Oszukowski, P.ła.
Ginekologia Polska 76(6): 436-442
2005
ISSN/ISBN: 0017-0011 PMID: 16149260 Document Number: 589211
Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration in women in preterm labor. We attempted to determine the effect of antibioticotherapy in mothers on congenital neonatal infection. The study group consisted of 1049 pregnant women with imminent preterm labor hospitalized in Clinics of The Research Institute Polish Mother's Memorial Hospital. 244 women delivered preterm and no significant difference in neonatal outcomes could be detected in two groups with intact membranes and preterm premature rupture of membranes. The results of this study do not support the routine use of antibiotic administration in women with preterm labor.